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Biomedical Science and Engineering

eISSN 2531-9892

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Editor-in-Chief: Valeria Chiono, Italy

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  • A novel human iPSC-based co-culture model to study neurocardiac interaction in vitro

    G. Cattelan, G. Gentile, C. Volani, L. S. Frommelt, A. Lavdas, L. Foco, M. De Bortoli, C. Altomare, L. Barile, S. Zacchigna, P. P. Pramstaller, I. Pichler, A. Zanon, A. Rossini
    17-11-2023
    https://doi.org/10.4081/bse.232
    268
    PDF: 202
  • Nebuloid: a novel in silico agent-based cell model

    P. Mancini, E. Botte, F. Biagini, C. Magliaro, A. Ahluwalia
    16-11-2023
    https://doi.org/10.4081/bse.225
    289
    PDF: 202
  • Stress-induced premature senescence in hiPSC-derived cardiomyocytes recapitulates aging-induced cardiac remodelling

    E. Lazzarini, A. M. Lodrini, M. Arici, S. Bolis, S. Vagni, S. Panella, A. Rendon-Angel, M. Saibene, A. Metallo, T. Torre, G. Vassalli, P. Ameri, C. Altomare, M. Rocchetti, L. Barile
    17-11-2023
    https://doi.org/10.4081/bse.230
    259
    PDF: 177
  • PDMS Substrates with tunable stiffness for cardiac mechanobiology investigation: A nanoindentation study

    Gianpaolo Serino, Andrea T. Lugas, Giacomo Bernava, Sara Ragazzini, Stefano Gabetti, Mara Terzini, Umberto Morbiducci, Alberto Audenino, Maurizio Pesce, Diana Massai
    29-09-2021
    https://doi.org/10.4081/bse.192
    494
    PDF: 402
  • A multi-purpose platform for the assessment of the pro-oxidative potential of silver nanoparticles

    L. Faccani, R. Bengalli, M. Gualtieri, F. C. Simeone, P. Mantecca, M. Blosi, A. L. Costa
    14-11-2023
    https://doi.org/10.4081/bse.210
    933
    PDF: 152
  • Study of bio-based nanomaterials inflammation potential in a zebrafish embryo model

    C. Bragato, R. Bengalli, A. Persico, R. Mazzotta, P. Bonfanti, M. Gualtieri, P. Mantecca
    17-11-2023
    https://doi.org/10.4081/bse.229
    254
    PDF: 150
  • European regulatory framework for the clinical translation of bioprinted scaffolds and tissues

    Licia Di Pietro, Alice Ravizza, Giovanni Vozzi, Andrés Diaz Lantada, Arti Ahluwalia, Carmelo De Maria
    14-02-2020
    https://doi.org/10.4081/bse.108
    946
    PDF: 487
  • Versatile electrical stimulator for providing cardiac-like electrical impulses in vitro

    Stefano Gabetti, Giovanni Putame, Federica Montrone, Giuseppe Isu, Anna Marsano, Alberto Audenino, Diana Massai
    14-02-2020
    https://doi.org/10.4081/bse.111
    868
    PDF: 359
  • Bone and gut microbiota crosstalk: A novel 3D in vitro approach

    Monica Mattioli Belmonte, Giorgia Cerqueni, Francesco Biagini, Marco Calvigioni, Emanuele Russello, Nunzia Paglione, Francesca Montemurro, Emilia Ghelardi, Giovanni Vozzi
    28-09-2021
    https://doi.org/10.4081/bse.134
    1336
    PDF: 324
  • Reconstituted epithelial corneal tissues for evaluation of drug delivery

    Susi Burgalassi, Erica Zucchetti, Eleonora Terreni, Daniela Monti, Silvia Tampucci, Patrizia Chetoni
    11-02-2020
    https://doi.org/10.4081/bse.82
    553
    PDF: 290
  • Real-time cellular impedance monitoring and imaging in a dual-flow bioreactor

    Ludovica Cacopardo, Joana Costa, Nicole Guazzelli, Serena Giusti, Sandro Meucci, Alessandro Corti, Giorgio Mattei, Arti Ahluwalia
    12-02-2020
    https://doi.org/10.4081/bse.104
    1505
    PDF: 336
  • Analysis of non-animal methods and models for research in cardiovascular disease

    Emanuele Gasparotti, Margherita Cioffi, Vincenzo Positano, Emanuele Vignali, Benigno Marco Fanni, Katia Capellini, Dorela Haxhiademi, Emiliano Costa, Sergio Berti, Luigi Landini, Simona Celi, Laura Gribaldo
    14-02-2020
    https://doi.org/10.4081/bse.112
    630
    PDF: 291
  • Phantoms in medicine: The case of ophthalmology

    Carmelo De Maria, Sara Iorio, Francesca Montemurro, Gabriele Maria Fortunato, Michela Ori, Vittoria Raffa, Giovanni Vozzi
    08-07-2019
    https://doi.org/10.4081/bse.61
    1257
    PDF: 505
    APPENDIX: 193
  • Acinus-on-a-chip microfluidic device with 3d spherical air-liquid interfaces

    N. Guazzelli, L. Cacopardo, P. Signorello, P. Singh, A. Ahluwalia
    15-11-2023
    https://doi.org/10.4081/bse.217
    353
    PDF: 202
  • A millifluidic-based 3D-platform as a useful tool for the efficacy of glaucoma therapeutic strategies

    Anna M. Bassi, Sara Tirendi, Sonia Scarfì, Mario Passalacqua, Vanessa Almonti, Stefania Vernazza
    28-09-2021
    https://doi.org/10.4081/bse.135
    1359
    PDF: 274
  • Alginate dialdehyde-gelatin bioinks exploiting internal gelation mechanism for cardiac tissue engineering

    E. Marcello, G. P. Stola, C. Paoletti, L. Nicoletti, V. Chiono
    14-11-2023
    https://doi.org/10.4081/bse.212
    892
    PDF: 178
  • A computational platform to assess the metabolic-electrophysiological behaviour of neurons cultured in monolayers

    R. Fabbri, A. Ahluwalia, C. Magliaro
    17-11-2023
    https://doi.org/10.4081/bse.227
    271
    PDF: 195
  • Development of an animal-free methodology for mechanical performance assessment of engineered skin substitutes

    Alessandra Aldieri, Mara Terzini, Diana Massai, Cristina Bignardi, Alberto Audenino
    12-02-2020
    https://doi.org/10.4081/bse.103
    1916
    PDF: 632
  • Patient-specific modelling for the assessment of the hemodynamics risk of failure in endovascular aneurysm repair

    Maurizio Lodi Rizzini, Paola Tasso, Anastasios Raptis, Miltiadis Matsagkas, Diego Gallo, Michalis Xenos, Umberto Morbiducci
    29-09-2021
    https://doi.org/10.4081/bse.175
    724
    PDF: 244
  • Drug-free antibacterial polymers for biomedical applications

    Ayesha Idrees, Patrícia Varela, Francesca Ruini, Jeddah Marie Vasquez, Jochen Salber, Udo Greiser, Wenxin Wang, Sean McMahon, Susanna Sartori, Gianluca Ciardelli, Valeria Chiono
    10-05-2018
    https://doi.org/10.4081/bse.39
    1902
    PDF: 734
  • Design and fabrication of an intestinal phantom

    P. Signorello, L. Cacopardo, N. Guazzelli, I. Nicolai, A. Ahluwalia
    15-11-2023
    https://doi.org/10.4081/bse.214
    416
    PDF: 134
  • In vitro model of the human esophageal epithelium by tissue engineering tools

    M. Spedicati, A. Zoso, I. Carmagnola, V. Chiono
    15-11-2023
    https://doi.org/10.4081/bse.215
    345
    PDF: 158
  • Injectable thermosensitive gels for the localized and controlled delivery of biomolecules in tissue engineering/regenerative medicine

    Monica Boffito, Arianna Grivet Brancot, Ornella Lima, Simona Bronco, Susanna Sartori, Gianluca Ciardelli
    09-07-2019
    https://doi.org/10.4081/bse.67
    938
    PDF: 590
  • Reconstituted epithelial tissues and native cornea: A comparison of the influence of surfactants on ocular permeability

    Erica Zucchetti, Daniela Monti, Patrizia Chetoni, Silvia Tampucci, Susi Burgalassi
    14-02-2020
    https://doi.org/10.4081/bse.123
    593
    PDF: 269
  • Polyvinyl alcohol/cellulose hydrogel as possible corneal stroma substitute in drug permeation tests

    Erica Zucchetti, Leonardo Ling, Daniela Monti, Patrizia Chetoni, Silvia Tampucci, Susi Burgalassi
    29-09-2021
    https://doi.org/10.4081/bse.203
    387
    PDF: 233
  • Toward scalable in vitro models: a novel experimental and computational pipeline for the identification of cellular metabolic parameters

    Piera Mancini, Ermes Botte, Chiara Magliaro, Arti Ahluwalia
    29-09-2021
    https://doi.org/10.4081/bse.179
    660
    PDF: 205
  • Engineering a dynamic model of the alveolar interface for the study of aerosol deposition

    Roberta Nossa, Joana Costa, Ludovica Cacopardo, Arti Ahluwalia
    14-02-2020
    https://doi.org/10.4081/bse.115
    712
    PDF: 376
  • Biomimetic air-liquid interface milli-bioreactor for skin tissue engineering applications

    B. Masante, S. Gabetti, D. Baruffaldi, S. Villata, A. Sanginario, A. L. Audenino, F. Frascella, D. Massai
    14-11-2023
    https://doi.org/10.4081/bse.208
    911
    PDF: 180
  • Nuclear receptor modulators: Catching information by machine learning

    Cecile Valsecchi, Francesca Grisoni, Viviana Consonni, Davide Ballabio, Roberto Todeschini
    29-09-2021
    https://doi.org/10.4081/bse.198
    370
    PDF: 210
  • A novel in silico tool for dose assessment in cell culture nanotoxicology

    Ermes Botte, Pietro Vagaggini, Joana Costa, Lara Faccani, Ilaria Zanoni, Anna Costa, Arti Ahluwalia
    29-09-2021
    https://doi.org/10.4081/bse.156
    490
    PDF: 287
  • Characterising the current provision of education and training courses relevant to the Replacement, Reduction and Refinement (Three Rs) of animals used for scientific purposes

    Adelaide Dura, Marcelle Holloway
    11-02-2020
    https://doi.org/10.4081/bse.88
    969
    PDF: 449
  • Engineering magneto-responsive core-shell microbeads for mimicking peristalsis and alveolar breathing in vitro

    Nicole Guazzelli, Ludovica Cacopardo, Arti Ahluwalia
    29-09-2021
    https://doi.org/10.4081/bse.173
    746
    PDF: 257
  • Biobanking and biomolecular resource research infrastructure: The Italian node

    Barbara Parodi
    12-02-2020
    https://doi.org/10.4081/bse.100
    348
    PDF: 232
  • In vitro models of human cardiac fibrotic tissue on bioartificial scaffolds

    Alice Zoso, Irene Carmagnola, Gerardina Ruocco, Mattia Spedicati, Valeria Chiono
    14-02-2020
    https://doi.org/10.4081/bse.122
    754
    PDF: 352
  • Development of in vitro intestinal barrier model for predictive pre-clinical evaluations

    A. M. A. Rando, L. P. Coppadoro, M. Poppa, C. Russo, S. Nicolò, M. Lombardi, C. Foglieni, G. B. Fiore, M. Soncini
    17-11-2023
    https://doi.org/10.4081/bse.231
    193
    PDF: 134
  • Promising 3D in vitro models for studying tumour heterogeneity and testing novel therapeutic approaches in pancreatic cancer

    Stefania Forciniti, Marta Cavo, Ilaria Dando, Elisa Dalla Pozza, Marta Palmieri, Loretta L. del Mercato
    29-09-2021
    https://doi.org/10.4081/bse.169
    696
    PDF: 259
  • In vitro human-relevant glioblastoma models as the novel frontier of nanomedicine screening

    A. Bezze, G. Ciardelli, C. Mattu
    16-11-2023
    https://doi.org/10.4081/bse.222
    209
    PDF: 135
  • Centro 3R: Organ and tissue sharing project

    Manuela Marcoli
    11-02-2020
    https://doi.org/10.4081/bse.96
    338
    PDF: 245
  • Clarifying mid-brain organoids: Application of the CLARITY protocol to unperfusable samples

    Chiara Magliaro, Arti Ahluwalia
    14-02-2020
    https://doi.org/10.4081/bse.113
    1134
    PDF: 458
  • In silico modeling of biochemical pathways

    Paolo Milazzo, Roberta Gori, Alessio Micheli, Lucia Nasti, Marco Podda
    28-09-2021
    https://doi.org/10.4081/bse.142
    1308
    PDF: 299
  • In vitro multi-level approaches to study cadmium neurotoxicity

    Marta Scrivani, Matilde Forcella, Federica Bovio, Alessia Bogni, Marco Fabbri, Laura Gribaldo, Sergio Andò, Pasquale Melchioretto, Maria Tringali, Paola Fusi, Chiara Urani
    29-09-2021
    https://doi.org/10.4081/bse.190
    319
    PDF: 240
  • Organoid culture systems: Products supporting one of the biggest revolutions in biological research

    Ryan Conder, Leon H. Chew, Fisal Elstone, Marianne Lankhorst, Adam Añonuevo, Salvatore Simmini, Wing Chang, Allen C. Eaves, Terry E. Thomas, Sharon A. Louis
    12-02-2020
    https://doi.org/10.4081/bse.102
    591
    PDF: 585
  • Effects of occupational exposure to glyphosate in winegrowers

    Melissa Ferrian, Antonella Annicchiarico, Mario Oliveri, Claudio Colosio, Emanuela Corsini, Alessandra Barassi, Giuseppe Mastrangelo, Emanuela Fadda, Manuela Peruzzi, Stefano Porru
    14-02-2020
    https://doi.org/10.4081/bse.110
    628
    PDF: 326
  • A novel in vitro culture system for the generation of controlled hydrodinamic stimuli

    Elia Pederzani, Lorenzo P. Coppadoro, Chiara Foglieni, Maria Lombardi, Monica Soncini, Gianfranco B. Fiore
    29-09-2021
    https://doi.org/10.4081/bse.187
    394
    PDF: 336
  • Towards reliable in vitro models. New bi-compartmental platforms for replicating tissue barriers

    Lorenzo P. Coppadoro, Elia Pederzani, Chiara Foglieni, Maria Lombardi, Gianfranco B. Fiore, Monica Soncini
    29-09-2021
    https://doi.org/10.4081/bse.166
    405
    PDF: 223
  • Cadmium elicits alterations in mitochondrial morphology and functionality in C3H10T1/2Cl8 mouse fibroblast cell

    Monica Oldani, Chiara Milani, Federico Gaboardi, Marta Manzoni, Anna M. Villa, Federico M. Stefanini, Pasquale Melchioretto, Eugenio Monti, Matilde Forcella, Chiara Urani, Paola Fusi
    29-09-2021
    https://doi.org/10.4081/bse.185
    292
    PDF: 183
  • The 3Rs: Reduction and refinement through a multivariate statistical analysis approach in a behavioural study to unveil anxiolytic effects of natural extracts of Tilia tomentosa

    Guendalina Olivero, Federica Turrini, Matteo Vergassola, Raffaella Boggia, Paola Zunin, Dario Donno, Gabriele Loris Beccaro, Massimo Grilli, Anna Pittaluga
    14-02-2020
    https://doi.org/10.4081/bse.116
    620
    PDF: 348
  • Teaching and training in substitutive approaches to animal testing: Commitment of the University of Genoa

    Anna Maria Bassi
    11-02-2020
    https://doi.org/10.4081/bse.81
    479
    PDF: 297
  • Ethical issues in Ph.D. training at the Politecnico di Milano

    Andrea Aliverti
    12-02-2020
    https://doi.org/10.4081/bse.80
    420
    PDF: 260
  • Global 3R approach and bioreactors in biomedical research

    L. Calvillo
    15-11-2023
    https://doi.org/10.4081/bse.216
    322
    PDF: 120
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  • Rigenera protocol: Elucidation of the mechanisms involved in wound healing
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  • A novel human iPSC-based co-culture model to study neurocardiac interaction in vitro
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  • A computational platform to assess the metabolic-electrophysiological behaviour of neurons cultured in monolayers
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  • Dynamic 3D culture promotes lymphoid tissue maturation and allows the study of Chronic Lymphocyitc Leukemia cells dissemination in vitro
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eISSN: 2531-9892

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