Vol. 1 No. 1 (2020)

Published: 14-02-2020

View Vol. 1 No. 1 (2020)

Editorials

Biomedical Science and Engineering: a new multidisciplinary journal dealing with modern regenerative medicine strategies

Valeria Chiono

https://doi.org/10.4081/bse.4

Published: 30 May 2016

838

PDF: 378
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The Italian Centro 3R: Mission and early achievements presented during the Second Annual Meeting

Arti Ahluwalia

https://doi.org/10.4081/bse.79

Published: 11 February 2020

413

PDF: 252
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Original Articles

Nerve guidance conduits based on bi-layer chitosan membranes for peripheral nerve regeneration

Francesca Ruini, Chiara Tonda-Turo, Stefania Raimondo, Pierluigi Tos, Pierfrancesco Pugliese, Stefano Geuna, Gianluca Ciardelli

https://doi.org/10.4081/bse.12

Published: 30 May 2016

1164

PDF: 466
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Injectable thermosensitive gels for the localized and controlled delivery of biomolecules in tissue engineering/regenerative medicine

Monica Boffito, Arianna Grivet Brancot, Ornella Lima, Simona Bronco, Susanna Sartori, Gianluca Ciardelli

https://doi.org/10.4081/bse.67

Published: 9 July 2019

836

PDF: 557
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Investigating the microenvironmental effects of scaffold chemistry and topology in human mesenchymal stromal cell/polymeric hollow microfiber constructs

Claudio Ricci, Luisa Trombi, Ilaria Soriga, Fabio Piredda, Mario Milazzo, Cesare Stefanini, Luca Bruschini, Giuseppe Perale, Gianni Pertici, Serena Danti

https://doi.org/10.4081/bse.10

Published: 30 May 2016

969

PDF: 449
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Layer-by-layer coating of stainless steel plates mediated by surface priming treatment to improve antithrombogenic properties

Irene Carmagnola, Tiziana Nardo, Francesca Boccafoschi, Valeria Chiono

https://doi.org/10.4081/bse.22

Published: 30 May 2016

764

PDF: 377
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Ethical issues in Ph.D. training at the Politecnico di Milano

Andrea Aliverti

https://doi.org/10.4081/bse.80

Published: 12 February 2020

373

PDF: 243
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Development of an animal-free methodology for mechanical performance assessment of engineered skin substitutes

Alessandra Aldieri, Mara Terzini, Diana Massai, Cristina Bignardi, Alberto Audenino

https://doi.org/10.4081/bse.103

Published: 12 February 2020

1834

PDF: 571
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Real-time cellular impedance monitoring and imaging in a dual-flow bioreactor

Ludovica Cacopardo, Joana Costa, Nicole Guazzelli, Serena Giusti, Sandro Meucci, Alessandro Corti, Giorgio Mattei, Arti Ahluwalia

https://doi.org/10.4081/bse.104

Published: 12 February 2020

1428

PDF: 311
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Teaching and training in substitutive approaches to animal testing: Commitment of the University of Genoa

Anna Maria Bassi

https://doi.org/10.4081/bse.81

Published: 11 February 2020

429

PDF: 275
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Reconstituted epithelial corneal tissues for evaluation of drug delivery

Susi Burgalassi, Erica Zucchetti, Eleonora Terreni, Daniela Monti, Silvia Tampucci, Patrizia Chetoni

https://doi.org/10.4081/bse.82

Published: 11 February 2020

485

PDF: 266
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In vitro microfluidic modelling of the human blood-brain-barrier microvasculature and testing of nanocarrier transport

Marco Campisi, Sharon W. L. Lee, Tatsuya Osaki, Luca Possenti, Clara Mattu, Giulia Adriani, Valeria Chiono, Roger D. Kamm

https://doi.org/10.4081/bse.105

Published: 12 February 2020

1954

PDF: 501
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Tissue engineered constructs for the replacement of laboratory animals: Biomimetics and microfluidics

Maria Grazia Cascone, Luigi Lazzeri, Elisabetta Rosellini

https://doi.org/10.4081/bse.83

Published: 11 February 2020

424

PDF: 262
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Quantification of the foreign body reaction by means of a miniaturized imaging window for intravital nonlinear microscopy

Claudio Conci, Emanuela Jacchetti, Tommaso Zandrini, Laura Sironi, Maddalena Collini, Giuseppe Chirico, Giulio Cerullo, Roberto Osellame, Manuela Teresa Raimondi

https://doi.org/10.4081/bse.106

Published: 14 February 2020

1511

PDF: 321
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Approaching 3R teaching in biomedical engineering

Valeria Chiono

https://doi.org/10.4081/bse.84

Published: 11 February 2020

452

PDF: 284
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Chitosan biopolymer: Alternative adhesion factor and scaffold matrix for 2D and 3D neuronal cultures

Donatella Di Lisa, Mariateresa Tedesco, Elena Dellacasa, Mattia Pesce, Tiziano Catelani, Paolo Massobrio, Roberto Raiteri, Sergio Martinoia, Laura Pastorino

https://doi.org/10.4081/bse.107

Published: 14 February 2020

1871

PDF: 392
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On the transferability of tissue engineering technologies to the design of tissue models

Gianluca Ciardelli

https://doi.org/10.4081/bse.85

Published: 11 February 2020

336

PDF: 223
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European regulatory framework for the clinical translation of bioprinted scaffolds and tissues

Licia Di Pietro, Alice Ravizza, Giovanni Vozzi, Andrés Diaz Lantada, Arti Ahluwalia, Carmelo De Maria

https://doi.org/10.4081/bse.108

Published: 14 February 2020

853

PDF: 442
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Use of an in vitro model of hepatic steatosis for studying the anti-oxidant and antisteatotic effects of fucoidan polysaccharides

Zeinab El Rashed, Hala Khalife, Adriana Voci, Elena Grasselli, Laura Canesi, Ilaria Demori

https://doi.org/10.4081/bse.109

Published: 14 February 2020

512

PDF: 276
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Biomechanical simulations and 3D printing for endovascular device testing

Michele Conti, Stefania Marconi, Ferdinando Auricchio

https://doi.org/10.4081/bse.86

Published: 11 February 2020

412

PDF: 256
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Computational molecular modelling as a platform for a deeper understanding of protein dynamics and rational drug design

Gianvito Grasso, Lorenzo Pallante, Jack A. Tuszynski, Umberto Morbiducci, Marco A. Deriu

https://doi.org/10.4081/bse.87

Published: 11 February 2020

566

PDF: 267
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Effects of occupational exposure to glyphosate in winegrowers

Melissa Ferrian, Antonella Annicchiarico, Mario Oliveri, Claudio Colosio, Emanuela Corsini, Alessandra Barassi, Giuseppe Mastrangelo, Emanuela Fadda, Manuela Peruzzi, Stefano Porru

https://doi.org/10.4081/bse.110

Published: 14 February 2020

583

PDF: 306
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Versatile electrical stimulator for providing cardiac-like electrical impulses in vitro

Stefano Gabetti, Giovanni Putame, Federica Montrone, Giuseppe Isu, Anna Marsano, Alberto Audenino, Diana Massai

https://doi.org/10.4081/bse.111

Published: 14 February 2020

759

PDF: 330
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Characterising the current provision of education and training courses relevant to the Replacement, Reduction and Refinement (Three Rs) of animals used for scientific purposes

Adelaide Dura, Marcelle Holloway

https://doi.org/10.4081/bse.88

Published: 11 February 2020

841

PDF: 412
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Swiss 3R Competence Centre: Promoting the 3Rs implementation

Chantra Eskes

https://doi.org/10.4081/bse.89

Published: 11 February 2020

308

PDF: 222
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Analysis of non-animal methods and models for research in cardiovascular disease

Emanuele Gasparotti, Margherita Cioffi, Vincenzo Positano, Emanuele Vignali, Benigno Marco Fanni, Katia Capellini, Dorela Haxhiademi, Emiliano Costa, Sergio Berti, Luigi Landini, Simona Celi, Laura Gribaldo

https://doi.org/10.4081/bse.112

Published: 14 February 2020

542

PDF: 269
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Advanced culture systems for ex vivo human vascular tissue conditioning

Gianfranco Beniamino Fiore, Simona Seminati, Lorenzo Pietro Coppadoro, Elia Pederzani, Marco Piola, Monica Soncini

https://doi.org/10.4081/bse.90

Published: 11 February 2020

406

PDF: 238
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Clarifying mid-brain organoids: Application of the CLARITY protocol to unperfusable samples

Chiara Magliaro, Arti Ahluwalia

https://doi.org/10.4081/bse.113

Published: 14 February 2020

1026

PDF: 421
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Application of two in vitro methods for the toxicity test of autogenous vaccines

Erika Molica Colella, Silvia Dotti, Riccardo Villa, Guerino Lombardi, Massimo Amadori

https://doi.org/10.4081/bse.114

Published: 14 February 2020

552

PDF: 265
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Refinement of laboratory animal welfare

Angelo Gazzano, Chiara Mariti

https://doi.org/10.4081/bse.91

Published: 11 February 2020

408

PDF: 333
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Pisa Biobank and Tuscany Regional Biorepository

Francesca Nocchi, Patrizia Urciuoli, Silvia Ursino, Elisa Biagi, Simone Lapi

https://doi.org/10.4081/bse.92

Published: 11 February 2020

456

PDF: 245
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Engineering a dynamic model of the alveolar interface for the study of aerosol deposition

Roberta Nossa, Joana Costa, Ludovica Cacopardo, Arti Ahluwalia

https://doi.org/10.4081/bse.115

Published: 14 February 2020

618

PDF: 338
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The 3Rs: Reduction and refinement through a multivariate statistical analysis approach in a behavioural study to unveil anxiolytic effects of natural extracts of Tilia tomentosa

Guendalina Olivero, Federica Turrini, Matteo Vergassola, Raffaella Boggia, Paola Zunin, Dario Donno, Gabriele Loris Beccaro, Massimo Grilli, Anna Pittaluga

https://doi.org/10.4081/bse.116

Published: 14 February 2020

572

PDF: 311
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QSAR models and their practical use. The experience of Kode

Alberto Manganaro

https://doi.org/10.4081/bse.93

Published: 11 February 2020

407

PDF: 364
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Bioreactors as physiologicallike in vitro models

Sara Mantero, Federica Boschetti

https://doi.org/10.4081/bse.94

Published: 11 February 2020

337

PDF: 246
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Health monitoring program for the control of laboratory animal diseases

Chiara Romano, Andrea Cacciamali, Silvia Dotti, Riccardo Villa

https://doi.org/10.4081/bse.117

Published: 14 February 2020

614

PDF: 290
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For an ethics of experimentation. Moral arguments supporting 3Rs

Franco Manti

https://doi.org/10.4081/bse.95

Published: 11 February 2020

311

PDF: 264
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Zebrafish as an alternative method for toxicological studies

Maria Sampieri, Riccardo Villa, Silvia Dotti

https://doi.org/10.4081/bse.118

Published: 14 February 2020

675

PDF: 316
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Assessment of an in vitro physiological relevant model to check therapeutic strategies for glaucoma

Sara Tirendi, Stefania Vernazza, Sergio Saccà, Anna Maria Bassi

https://doi.org/10.4081/bse.120

Published: 14 February 2020

616

PDF: 317
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Centro 3R: Organ and tissue sharing project

Manuela Marcoli

https://doi.org/10.4081/bse.96

Published: 11 February 2020

291

PDF: 221
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Renewing potency assays: Moving forward from traditional methods

Francesco Nevelli

https://doi.org/10.4081/bse.97

Published: 12 February 2020

404

PDF: 329
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SG-2: A promising lipolytic and pro-autophagic hit-compound to treat Alzheimer's disease

Massimiliano Runfola, Michele Perni, Simona Sestito, Grazia Chiellini, Michele Vendruscolo, Simona Rapposelli

https://doi.org/10.4081/bse.121

Published: 14 February 2020

587

PDF: 265
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In vitro models of human cardiac fibrotic tissue on bioartificial scaffolds

Alice Zoso, Irene Carmagnola, Gerardina Ruocco, Mattia Spedicati, Valeria Chiono

https://doi.org/10.4081/bse.122

Published: 14 February 2020

651

PDF: 317
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Platelet rich plasma enhancement of skin regeneration in an ex vivo human experimental model

Giovanni Nicoletti, Marco Saler, Laura Villani, Agnese Rumolo, Marco Mario Tresoldi, Angela Faga

https://doi.org/10.4081/bse.98

Published: 12 February 2020

307

PDF: 193
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Neurophysiological models of animal sentience

Michele Panzera

https://doi.org/10.4081/bse.99

Published: 12 February 2020

323

PDF: 232
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Reconstituted epithelial tissues and native cornea: A comparison of the influence of surfactants on ocular permeability

Erica Zucchetti, Daniela Monti, Patrizia Chetoni, Silvia Tampucci, Susi Burgalassi

https://doi.org/10.4081/bse.123

Published: 14 February 2020

538

PDF: 242
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Biobanking and biomolecular resource research infrastructure: The Italian node

Barbara Parodi

https://doi.org/10.4081/bse.100

Published: 12 February 2020

303

PDF: 210
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Hydrogel-based platforms to mimic in vivo drug diffusion: A multicenter research

Paola Petrini, Daniela Pacheco, Francesco Briatico Vangosa, Cosmin S. Butnarasu, Livia Visai, Orietta Monticelli, Laura Pastorino, Sonja Visentin

https://doi.org/10.4081/bse.101

Published: 12 February 2020

460

PDF: 278
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Organoid culture systems: Products supporting one of the biggest revolutions in biological research

Ryan Conder, Leon H. Chew, Fisal Elstone, Marianne Lankhorst, Adam Añonuevo, Salvatore Simmini, Wing Chang, Allen C. Eaves, Terry E. Thomas, Sharon A. Louis

https://doi.org/10.4081/bse.102

Published: 12 February 2020

522

PDF: 552
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Reviews

Manufacturability and mechanical testing considerations of metallic scaffolds fabricated using selective laser melting: a review

Swee Leong Sing, Yixin Miao, Florencia Edith Wiria, Wai Yee Yeong

https://doi.org/10.4081/bse.11

Published: 30 May 2016

1268

PDF: 748
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Drug-free antibacterial polymers for biomedical applications

Ayesha Idrees, PatrÃcia Varela, Francesca Ruini, Jeddah Marie Vasquez, Jochen Salber, Udo Greiser, Wenxin Wang, Sean McMahon, Susanna Sartori, Gianluca Ciardelli, Valeria Chiono

https://doi.org/10.4081/bse.39

Published: 10 May 2018

1737

PDF: 706
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Phantoms in medicine: The case of ophthalmology

Carmelo De Maria, Sara Iorio, Francesca Montemurro, Gabriele Maria Fortunato, Michela Ori, Vittoria Raffa, Giovanni Vozzi

https://doi.org/10.4081/bse.61

Published: 8 July 2019

1191

PDF: 482

APPENDIX: 182
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- APPENDIX

Abstract Book

Drug-Free Antibacterial Technology for Medical Applications - First Cambridge International Conference - December 14th, 2018 - Cambridge, UK

Valeria Chiono, Jochen Salber

https://doi.org/10.4081/bse.66

Published: 25 February 2019

503

PDF: 494
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