Platelet rich plasma enhancement of skin regeneration in an ex vivo human experimental model

Published: 12 February 2020
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An original ex vivo wounded skin culture protocol using autologous Platelet Rich Plasma (PRP) and enriched Dulbecco’s Modified Eagle’s Medium demonstrated a favourable modulation of the epithelial cells and fibroblasts proliferation, a relevant antiinflammatory action and a favourable modulation of the re-organization of collagen and elastic fibres. The step by step regenerative effects of PRP on human skin wound repair and regeneration process was observed over a period of 10 days.

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Nicoletti, G., Saler, M., Villani, L., Rumolo, A., Tresoldi, M. M., & Faga, A. (2020). Platelet rich plasma enhancement of skin regeneration in an ex vivo human experimental model. Biomedical Science and Engineering, 1(1). https://doi.org/10.4081/bse.98

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