https://doi.org/10.4081/bse.176
Development of a multiscale testing method for the reduction of soft biological tissues waste during mechanical characterization
Published: 29 September 2021
Abstract Views: 657
PDF: 210
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Two biaxial mechanical test methods were devised to compare their suitability for the mechanical characterization of soft biological tissues with the least possible tissue waste. Nanoindentation was used to explore the microscopic properties of the tissue and to overcome the macroscopic test limitations.
1. Negishi J, Hashimoto Y, Yamashita A, Zhang Y, Kimura T, Kishida A, Funamoto S. Evaluation of small-diameter vascular grafts reconstructed from decellularized aorta sheets. J Biomed Mater Res A 2017;105:1293-8.
2. Hiester ED, Sacks MS. Optimal bovine pericardial tissue selection sites. I. Fiber architecture and tissue thickness measurements. J Biomed Mater Res 1998;39:207–14.
3. Hiester ED, Sacks MS. Optimal bovine pericardial tissue selection sites. II. Cartographic analysis. J Biomed Mater Res 1998;39:215–221.
4. Billiar KL, Sacks MS. Biaxial mechanical properties of the natural and glutaraldehyde treated aortic valve cusp--Part I: Experimental results. J Biomech Eng 2000;122:23-30.
5. Sun W, Sacks MS, Sellaro TL, et al. Biaxial mechanical response of bioprosthetic heart valve biomaterials to high in-plane shear. ASME. J Biomech Eng 2003;125:372–80.
6. Sacks MS, Sun W. Multiaxial mechanical behavior of biological materials. Annu Rev Biomed Eng 2003;5:251-84.
2. Hiester ED, Sacks MS. Optimal bovine pericardial tissue selection sites. I. Fiber architecture and tissue thickness measurements. J Biomed Mater Res 1998;39:207–14.
3. Hiester ED, Sacks MS. Optimal bovine pericardial tissue selection sites. II. Cartographic analysis. J Biomed Mater Res 1998;39:215–221.
4. Billiar KL, Sacks MS. Biaxial mechanical properties of the natural and glutaraldehyde treated aortic valve cusp--Part I: Experimental results. J Biomech Eng 2000;122:23-30.
5. Sun W, Sacks MS, Sellaro TL, et al. Biaxial mechanical response of bioprosthetic heart valve biomaterials to high in-plane shear. ASME. J Biomech Eng 2003;125:372–80.
6. Sacks MS, Sun W. Multiaxial mechanical behavior of biological materials. Annu Rev Biomed Eng 2003;5:251-84.
How to Cite
Lugas, A. T., Serino, G., Terzini, M., Bignardi, C., & Audenino, A. L. (2021). Development of a multiscale testing method for the reduction of soft biological tissues waste during mechanical characterization. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.176
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Most read articles by the same author(s)
- Alessandra Aldieri, Mara Terzini, Diana Massai, Cristina Bignardi, Alberto Audenino, Development of an animal-free methodology for mechanical performance assessment of engineered skin substitutes , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Gianpaolo Serino, Andrea T. Lugas, Giacomo Bernava, Sara Ragazzini, Stefano Gabetti, Mara Terzini, Umberto Morbiducci, Alberto Audenino, Maurizio Pesce, Diana Massai, PDMS Substrates with tunable stiffness for cardiac mechanobiology investigation: A nanoindentation study , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Federico A. Bologna, Mara Terzini, Andrea T. Lugas, Alberto L. Audenino, Minimum performance level definition for bone plate testing according to standard: A preliminary study , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Simone Borrelli, Giovanni Putame, Mara Terzini, Andrea Ferro, Stefano Marone, Cristina Bignardi, Alberto L. Audenino, Total and local experimental validation of a lumbar spine numerical model to enhance the orthopaedic management of spinal metastases , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
Similar Articles
- Massimiliano Runfola, Michele Perni, Simona Sestito, Grazia Chiellini, Michele Vendruscolo, Simona Rapposelli, SG-2: A promising lipolytic and pro-autophagic hit-compound to treat Alzheimer's disease , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Maria Sampieri, Riccardo Villa, Silvia Dotti, Zebrafish as an alternative method for toxicological studies , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Tommaso Sbrana, IVTech: The next generation of in vitro models , Biomedical Science and Engineering: Vol. 3 No. 1 (2022)
- Federica Bovio, Barbara Sciandrone, Chiara Urani, Paola Fusi, Matilde Forcella, Maria Elena Regonesi, Superoxide dismutase 1 (SOD1) and cadmium: a three models approach to the comprehension of its neurotoxic effects , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Giorgia Cerqueni, Annachiara Scalzone, Xiao Nong Wang, Caterina Licini, Kenny Dalgarno, Ana Marina Ferreira-Duarte, Piergiorgio Gentile, Monica Mattioli Belmonte, An osteochondral bio-engineered model to in vitro mimicking osteoarthritis , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Guendalina Olivero, Federica Turrini, Matteo Vergassola, Raffaella Boggia, Paola Zunin, Dario Donno, Gabriele Loris Beccaro, Massimo Grilli, Anna Pittaluga, The 3Rs: Reduction and refinement through a multivariate statistical analysis approach in a behavioural study to unveil anxiolytic effects of natural extracts of Tilia tomentosa , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Deyanira Contartese, Francesca Salamanna, Veronica Borsari, Stefania Pagani, Maria Sartori, Lucia Martini, Giovanni Barbanti Brodano, Alessandro Gasbarrini, Milena Fini, Development and characterization of a novel human 3D model of bone metastasis from breast carcinoma in vitro cultured , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Giuseppe Valerio De Gaetano, Germana Lentini, Roberta Galbo, Francesco Coppolino, Agata Famà, Giuseppe Teti, An in vitro enterocyte cell-like model to study Group B streptococci internalization , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Erika Molica Colella, Silvia Dotti, Riccardo Villa, Guerino Lombardi, Massimo Amadori, Application of two in vitro methods for the toxicity test of autogenous vaccines , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Melissa Ferrian, Antonella Annicchiarico, Mario Oliveri, Claudio Colosio, Emanuela Corsini, Alessandra Barassi, Giuseppe Mastrangelo, Emanuela Fadda, Manuela Peruzzi, Stefano Porru, Effects of occupational exposure to glyphosate in winegrowers , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
You may also start an advanced similarity search for this article.
