https://doi.org/10.4081/bse.122
In vitro models of human cardiac fibrotic tissue on bioartificial scaffolds
Published: 14 February 2020
Abstract Views: 680
PDF: 333
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Cardiac infarction is a global burden worldwide that leads to fibrotic and not contractile myocardial tissue. In this work, in vitro models of infarcted tissue were developed as tools to test novel therapies for cardiac regeneration in the future. Human cardiac fibroblasts were cultured on scaffolds, with different compositions and architectures, as to mimic structural and chemical features of infarcted cardiac tissue. Early findings from in vitro cell tests were reported, showing an enhancement of cell attachment and proliferation in the case of bioartificial scaffolds, i.e. scaffolds based on a synthetic and a bioactive polymer.
How to Cite
Zoso, A., Carmagnola, I., Ruocco, G., Spedicati, M., & Chiono, V. (2020). In vitro models of human cardiac fibrotic tissue on <i>bioartificial</i> scaffolds. Biomedical Science and Engineering, 1(1). https://doi.org/10.4081/bse.122
Copyright (c) 2019 The Authors
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Most read articles by the same author(s)
- Marco Campisi, Sharon W. L. Lee, Tatsuya Osaki, Luca Possenti, Clara Mattu, Giulia Adriani, Valeria Chiono, Roger D. Kamm, In vitro microfluidic modelling of the human blood-brain-barrier microvasculature and testing of nanocarrier transport , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Ayesha Idrees, PatrÃcia Varela, Francesca Ruini, Jeddah Marie Vasquez, Jochen Salber, Udo Greiser, Wenxin Wang, Sean McMahon, Susanna Sartori, Gianluca Ciardelli, Valeria Chiono, Drug-free antibacterial polymers for biomedical applications , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Valeria Chiono, Biomedical Science and Engineering: a new multidisciplinary journal dealing with modern regenerative medicine strategies , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Irene Carmagnola, Tiziana Nardo, Francesca Boccafoschi, Valeria Chiono, Layer-by-layer coating of stainless steel plates mediated by surface priming treatment to improve antithrombogenic properties , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Valeria Chiono, Jochen Salber, Drug-Free Antibacterial Technology for Medical Applications - First Cambridge International Conference - December 14th, 2018 - Cambridge, UK , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Valeria Chiono, Approaching 3R teaching in biomedical engineering , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
Similar Articles
- Emanuele Gasparotti, Margherita Cioffi, Vincenzo Positano, Emanuele Vignali, Benigno Marco Fanni, Katia Capellini, Dorela Haxhiademi, Emiliano Costa, Sergio Berti, Luigi Landini, Simona Celi, Laura Gribaldo, Analysis of non-animal methods and models for research in cardiovascular disease , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Gregorio Marchiori, Melania Maglio, Lucia Martini, Andrea Visani, Stefano Zaffagnini, Milena Fini, View the meniscus: MicroCT strategies for enhancing microstructure visualization , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Simone Borrelli, Giovanni Putame, Mara Terzini, Andrea Ferro, Stefano Marone, Cristina Bignardi, Alberto L. Audenino, Total and local experimental validation of a lumbar spine numerical model to enhance the orthopaedic management of spinal metastases , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Nicole Guazzelli, Ludovica Cacopardo, Arti Ahluwalia, Engineering magneto-responsive core-shell microbeads for mimicking peristalsis and alveolar breathing in vitro , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Stefania Forciniti, Marta Cavo, Ilaria Dando, Elisa Dalla Pozza, Marta Palmieri, Loretta L. del Mercato, Promising 3D in vitro models for studying tumour heterogeneity and testing novel therapeutic approaches in pancreatic cancer , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Claudio Conci, Emanuela Jacchetti, Tommaso Zandrini, Laura Sironi, Maddalena Collini, Giuseppe Chirico, Giulio Cerullo, Roberto Osellame, Manuela Teresa Raimondi, Quantification of the foreign body reaction by means of a miniaturized imaging window for intravital nonlinear microscopy , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Andrea Aliverti, Ethical issues in Ph.D. training at the Politecnico di Milano , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Ermes Botte, Pietro Vagaggini, Joana Costa, Lara Faccani, Ilaria Zanoni, Anna Costa, Arti Ahluwalia, A novel in silico tool for dose assessment in cell culture nanotoxicology , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Daniele Bianchi, Daniele Bissacco, Maurizio Domanin, Santi Trimarchi, Rodrigo Romarowski, Stefania Marconi, Ferdinando Auricchio, Michele Conti, Coupling in silico and ex vivo porcine model for the evaluation of biomechanical impact of TEVAR , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Andrea Andolfi, Pietro Arnaldi, Donatella Di Lisa, Sergio Martinoia, Laura Pastorino, Ink-jet printed chitosan precise patterning for engineered 2D neuronal networks , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
You may also start an advanced similarity search for this article.
