https://doi.org/10.4081/bse.122
In vitro models of human cardiac fibrotic tissue on bioartificial scaffolds
Published: 14 February 2020
Abstract Views: 680
PDF: 333
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Cardiac infarction is a global burden worldwide that leads to fibrotic and not contractile myocardial tissue. In this work, in vitro models of infarcted tissue were developed as tools to test novel therapies for cardiac regeneration in the future. Human cardiac fibroblasts were cultured on scaffolds, with different compositions and architectures, as to mimic structural and chemical features of infarcted cardiac tissue. Early findings from in vitro cell tests were reported, showing an enhancement of cell attachment and proliferation in the case of bioartificial scaffolds, i.e. scaffolds based on a synthetic and a bioactive polymer.
How to Cite
Zoso, A., Carmagnola, I., Ruocco, G., Spedicati, M., & Chiono, V. (2020). In vitro models of human cardiac fibrotic tissue on <i>bioartificial</i> scaffolds. Biomedical Science and Engineering, 1(1). https://doi.org/10.4081/bse.122
Copyright (c) 2019 The Authors
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Most read articles by the same author(s)
- Marco Campisi, Sharon W. L. Lee, Tatsuya Osaki, Luca Possenti, Clara Mattu, Giulia Adriani, Valeria Chiono, Roger D. Kamm, In vitro microfluidic modelling of the human blood-brain-barrier microvasculature and testing of nanocarrier transport , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Ayesha Idrees, PatrÃcia Varela, Francesca Ruini, Jeddah Marie Vasquez, Jochen Salber, Udo Greiser, Wenxin Wang, Sean McMahon, Susanna Sartori, Gianluca Ciardelli, Valeria Chiono, Drug-free antibacterial polymers for biomedical applications , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Valeria Chiono, Biomedical Science and Engineering: a new multidisciplinary journal dealing with modern regenerative medicine strategies , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Irene Carmagnola, Tiziana Nardo, Francesca Boccafoschi, Valeria Chiono, Layer-by-layer coating of stainless steel plates mediated by surface priming treatment to improve antithrombogenic properties , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Valeria Chiono, Jochen Salber, Drug-Free Antibacterial Technology for Medical Applications - First Cambridge International Conference - December 14th, 2018 - Cambridge, UK , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Valeria Chiono, Approaching 3R teaching in biomedical engineering , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
Similar Articles
- Elena Delgrosso, Gaia Martina Sarcinelli, Federica Riva, Federica Riva, Franca Scocozza, Michele Conti, Ian Postuma, Silva Bortolussi, Cinzia Ferrari, Bioprinting for osteosarcoma model: Methodological aspects and experimental applications , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Roberta Nossa, Joana Costa, Ludovica Cacopardo, Arti Ahluwalia, Engineering a dynamic model of the alveolar interface for the study of aerosol deposition , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Salvatore Simmini, Allen C. Eaves, Sharon A. Louis, Wing Chang, Human pluripotent stem cell-derived organoids and their potential to reduce the use of animal models in research , Biomedical Science and Engineering: Vol. 3 No. 1 (2022)
- Francesco Nevelli, Renewing potency assays: Moving forward from traditional methods , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Erika Molica Colella, Silvia Dotti, Riccardo Villa, Guerino Lombardi, Massimo Amadori, Application of two in vitro methods for the toxicity test of autogenous vaccines , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Stefania Blasa, Valentina Pastori, Alessia D'Aloia, Marzia M. Lecchi, Differentiated neuroblastoma F-11 cells as an alternative in vitro model to dorsal root ganglion neurons , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Ludovica Cacopardo, Joana Costa, Nicole Guazzelli, Serena Giusti, Sandro Meucci, Alessandro Corti, Giorgio Mattei, Arti Ahluwalia, Real-time cellular impedance monitoring and imaging in a dual-flow bioreactor , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Anna M. Bassi, Sara Tirendi, Sonia Scarfì, Mario Passalacqua, Vanessa Almonti, Stefania Vernazza, A millifluidic-based 3D-platform as a useful tool for the efficacy of glaucoma therapeutic strategies , Biomedical Science and Engineering: Vol. 3 No. 1 (2022)
- E. Marcello, G. P. Stola, C. Paoletti, L. Nicoletti, V. Chiono, Alginate dialdehyde-gelatin bioinks exploiting internal gelation mechanism for cardiac tissue engineering , Biomedical Science and Engineering: Vol. 4 No. 1 (2023)
- Silvia Bolognin, Lisa M. Smits, Sarah L. Nickels, Stefano Magni, Paul Antony, Kamil Grzyb, Rejko Krüger, Alexander Skupin, Jens C. Schwamborn, A new brain organoid model to study Parkinson's disease , Biomedical Science and Engineering: Vol. 3 No. 1 (2022)
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
