https://doi.org/10.4081/bse.97
Renewing potency assays: Moving forward from traditional methods
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Merck is global market leader in the fertility and growth hormone deficiency treatment. The quality control analytical panels for each new produced batch envisage the potency quantification that is estimated using a dedicated in vivo assay. Indeed, no in vitro methods for gonadotropin potency quantification are available in any pharmacopoeia. Merck Ivrea started a project to replace the in vivo assays with in vitro assays able to mimic the physiological mechanism of action of each gonadotropin and growth hormone.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Licia Di Pietro, Alice Ravizza, Giovanni Vozzi, Andrés Diaz Lantada, Arti Ahluwalia, Carmelo De Maria, European regulatory framework for the clinical translation of bioprinted scaffolds and tissues , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Melissa Ferrian, Antonella Annicchiarico, Mario Oliveri, Claudio Colosio, Emanuela Corsini, Alessandra Barassi, Giuseppe Mastrangelo, Emanuela Fadda, Manuela Peruzzi, Stefano Porru, Effects of occupational exposure to glyphosate in winegrowers , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Guendalina Olivero, Federica Turrini, Matteo Vergassola, Raffaella Boggia, Paola Zunin, Dario Donno, Gabriele Loris Beccaro, Massimo Grilli, Anna Pittaluga, The 3Rs: Reduction and refinement through a multivariate statistical analysis approach in a behavioural study to unveil anxiolytic effects of natural extracts of Tilia tomentosa , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Maria Sampieri, Riccardo Villa, Silvia Dotti, Zebrafish as an alternative method for toxicological studies , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Chiara Magliaro, Arti Ahluwalia, Clarifying mid-brain organoids: Application of the CLARITY protocol to unperfusable samples , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Monica Mattioli Belmonte, Giorgia Cerqueni, Francesco Biagini, Marco Calvigioni, Emanuele Russello, Nunzia Paglione, Francesca Montemurro, Emilia Ghelardi, Giovanni Vozzi, Bone and gut microbiota crosstalk: A novel 3D in vitro approach , Biomedical Science and Engineering: Vol. 3 No. 1 (2022)
- Anna M. Bassi, Sara Tirendi, Sonia Scarfì, Mario Passalacqua, Vanessa Almonti, Stefania Vernazza, A millifluidic-based 3D-platform as a useful tool for the efficacy of glaucoma therapeutic strategies , Biomedical Science and Engineering: Vol. 3 No. 1 (2022)
- Flaminia Aliberti, Lorenza Rinvenuto, Giada Loi, Laura Benedetti, Franca Scocozza, Flavio Lorenzo Ronzoni, Maurilio Sampaolesi, Gabriella Cusella, Michele Conti, Gabriele Ceccarelli, Comparative analysis of different hydrogels for the bioprinting of 3D in vitro skeletal muscle models , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Désirée Baruffaldi, Marta Canta, Candido Fabrizio Pirri, Francesca Frascella, Development of in vitro 3D culture system to mimic lung cancer tissue , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Stefania Blasa, Valentina Pastori, Alessia D'Aloia, Marzia M. Lecchi, Differentiated neuroblastoma F-11 cells as an alternative in vitro model to dorsal root ganglion neurons , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
You may also start an advanced similarity search for this article.
