https://doi.org/10.4081/bse.167
An in vitro enterocyte cell-like model to study Group B streptococci internalization
Published: 29 September 2021
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
We used a 2D in vitro growth model of Caco2 cells to study invasion of Streptococcus agalactiae. This model can be useful for evaluating the virulence of the most relevant enteric pathogens.
Hon KL, Chan KH, Ko PL, et al. Late Onset Streptococcus agalactiae Meningitis following Early Onset Septicemia: A Preventable Disease? Case Rep Ped 2017;2017:8418105.
Snoeck V, Goddeeris B, Cox E. The role of enterocytes in the intestinal barrier function and antigen uptake. Microbes Infect 2005;7:997-1004.
Natoli M, Leoni BD, D'Agnano I, et al. Cell growing density affects the structural and functional properties of Caco2 differentiated monolayer. J Cell Physiol 2011;226:1531-43.
De Gaetano GV, Pietrocola G, Romeo L, et al. The Streptococcus agalactiae cell wall-anchored protein PbsP mediates adhesion to and invasion of epithelial cells by exploiting the host vitronectin/av integrin axis. Mol Microbiol2018;110:82-94.
Zaas DW, Swan ZD, Brown BJ, et al. Counteracting signaling activities in lipid rafts associated with the invasion of lung epithelial cells by Pseudomonas aeruginosa. J Biol Chem 2009;284:9955-64.
How to Cite
De Gaetano, G. V. ., Lentini, G., Galbo, R., Coppolino, F., Famà, A., & Teti, G. (2021). An <em>in vitro</em> enterocyte cell-like model to study Group B streptococci internalization. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.167
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