https://doi.org/10.4081/bse.117
Health monitoring program for the control of laboratory animal diseases
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Pathogens present in the environment are the biggest source of diseases and epidemics in the breeding of laboratory animals. In fact, the presence of microorganisms can critically influence the animal health status and, consequently, the validity and reproducibility of experimental data. In accordance with the 3Rs principle (Refinement, Reduction, Replacement), this study is part of the Refinement concept. The FELASA guidelines, formulated with the aim of guaranteeing the best animal health state, are a valid support for researchers. In this preliminary study, health-monitoring program was carried out within the breeding of laboratory animals in IZSLER facility. The main murine viruses were analyzed through molecular biology techniques (PCR, RT-PCR) and enzyme immunoassays (indirect ELISA). The established surveillance program steadily guarantees animal health and ensures the most controlled environmental and sanitary conditions. Further investigations will be needed to develop virus control strategies.
How to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Most read articles by the same author(s)
- Maria Sampieri, Riccardo Villa, Silvia Dotti, Zebrafish as an alternative method for toxicological studies , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Giuseppe Guagliano, Manuela Legnardim, Cristina Volpini, Nora Bloise, Silvia Dotti, Riccardo Villa, Livia Visai, Paola Petrini, Drug-induced hepatotoxicity studied in a 3D, in vitro model of the liver , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Erika Molica Colella, Silvia Dotti, Riccardo Villa, Guerino Lombardi, Massimo Amadori, Application of two in vitro methods for the toxicity test of autogenous vaccines , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Andrea Cacciamali, Chiara Romano, Martina Angela Checco, Riccardo Villa, Detection of pathogens from environmental samples for the evaluation of the health status of laboratory animals , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Maria Sampieri, Erika Molica Colella, Silvia Dotti, Chilled storage of zebrafish embryos: Development of an efficient protocol , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
Similar Articles
- Sara Mantero, Federica Boschetti, Bioreactors as physiologicallike in vitro models , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Nicolò Cacocciola, Matteo Parmeggiani, Matteo Segantini, Alessio Verna, Désirée Baruffaldi, Simona Villata, Francesca Frascella, Simone Luigi Marasso, Giancarlo Canavese, Matteo Cocuzza, Fabrizio Candido Pirri, A programmable culture platform for stimulation and in situ sensing of lung epithelial cells , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Erika Molica Colella, Silvia Dotti, Riccardo Villa, Guerino Lombardi, Massimo Amadori, Application of two in vitro methods for the toxicity test of autogenous vaccines , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Silvia Bolognin, Lisa M. Smits, Sarah L. Nickels, Stefano Magni, Paul Antony, Kamil Grzyb, Rejko Krüger, Alexander Skupin, Jens C. Schwamborn, A new brain organoid model to study Parkinson's disease , Biomedical Science and Engineering: Vol. 3 No. 1 (2022)
- Emanuele Gasparotti, Margherita Cioffi, Vincenzo Positano, Emanuele Vignali, Benigno Marco Fanni, Katia Capellini, Dorela Haxhiademi, Emiliano Costa, Sergio Berti, Luigi Landini, Simona Celi, Laura Gribaldo, Analysis of non-animal methods and models for research in cardiovascular disease , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Claudio Conci, Emanuela Jacchetti, Tommaso Zandrini, Laura Sironi, Maddalena Collini, Giuseppe Chirico, Giulio Cerullo, Roberto Osellame, Manuela Teresa Raimondi, Quantification of the foreign body reaction by means of a miniaturized imaging window for intravital nonlinear microscopy , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Désirée Baruffaldi, Marta Canta, Candido Fabrizio Pirri, Francesca Frascella, Development of in vitro 3D culture system to mimic lung cancer tissue , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Daniele Bianchi, Daniele Bissacco, Maurizio Domanin, Santi Trimarchi, Rodrigo Romarowski, Stefania Marconi, Ferdinando Auricchio, Michele Conti, Coupling in silico and ex vivo porcine model for the evaluation of biomechanical impact of TEVAR , Biomedical Science and Engineering: Vol. 2 No. 1 (2021)
- Michele Panzera, Neurophysiological models of animal sentience , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
- Gianluca Ciardelli, On the transferability of tissue engineering technologies to the design of tissue models , Biomedical Science and Engineering: Vol. 1 No. 1 (2020)
You may also start an advanced similarity search for this article.
