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  The 3Rs: Reduction and refinement through a multivariate statistical analysis approach in a behavioural study to unveil anxiolytic effects of natural extracts of Tilia tomentosa

  Guendalina Olivero, Federica Turrini, Matteo Vergassola, Raffaella Boggia, Paola Zunin, Dario Donno, Gabriele Loris Beccaro, Massimo Grilli, Anna Pittaluga

  14-02-2020

  Published: 14 February 2020

  572

  PDF: 311
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  Refinement of laboratory animal welfare

  Angelo Gazzano, Chiara Mariti

  11-02-2020

  Published: 11 February 2020

  408

  PDF: 333
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  Health monitoring program for the control of laboratory animal diseases

  Chiara Romano, Andrea Cacciamali, Silvia Dotti, Riccardo Villa

  14-02-2020

  Published: 14 February 2020

  614

  PDF: 290
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  Characterising the current provision of education and training courses relevant to the Replacement, Reduction and Refinement (Three Rs) of animals used for scientific purposes

  Adelaide Dura, Marcelle Holloway

  11-02-2020

  Published: 11 February 2020

  841

  PDF: 412
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  Zebrafish as an alternative method for toxicological studies

  Maria Sampieri, Riccardo Villa, Silvia Dotti

  14-02-2020

  Published: 14 February 2020

  675

  PDF: 316
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  European regulatory framework for the clinical translation of bioprinted scaffolds and tissues

  Licia Di Pietro, Alice Ravizza, Giovanni Vozzi, Andrés Diaz Lantada, Arti Ahluwalia, Carmelo De Maria

  14-02-2020

  Published: 14 February 2020

  853

  PDF: 442
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  Application of two in vitro methods for the toxicity test of autogenous vaccines

  Erika Molica Colella, Silvia Dotti, Riccardo Villa, Guerino Lombardi, Massimo Amadori

  14-02-2020

  Published: 14 February 2020

  552

  PDF: 265
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  Bioreactors as physiologicallike in vitro models

  Sara Mantero, Federica Boschetti

  11-02-2020

  Published: 11 February 2020

  337

  PDF: 246
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  The fantastic voyage of solid lipid nanoparticles from the lung to the brain: non-invasive tomographic imaging as a feasible refinement process

  G. Terribile, S. Di Girolamo, E. Donzelli, F. Re, P. Gasco, G. Sancini

  16-11-2023

  Published: 16 November 2023

  175

  PDF: 119
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  Application of reduction and refinement principles in the evaluation of prodromal markers of Parkinson’s disease in a progressive neurotoxic mouse model using multi-tracer PET imaging

  M. Tassan Mazzocco, S. Belloli, A. Pinna, M. Serra, M. Morelli, R. M. Moresco

  16-11-2023

  Published: 16 November 2023

  174

  PDF: 98
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  Norecopa: A database of global 3R resources for better Science

  Adrian J. Smith

  29-09-2021

  Published: 29 September 2021

  1286

  PDF: 293
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  The Italian Centro 3R: Mission and early achievements presented during the Second Annual Meeting

  Arti Ahluwalia

  11-02-2020

  Published: 11 February 2020

  413

  PDF: 252
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  Detection of pathogens from environmental samples for the evaluation of the health status of laboratory animals

  Andrea Cacciamali, Chiara Romano, Martina Angela Checco, Riccardo Villa

  29-09-2021

  Published: 29 September 2021

  479

  PDF: 283