Materials for bone regeneration: Current types, bioactive mechanism and updated investigations

  • Yuqi He Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Wei He Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Yubo Fan Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing; Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
  • Xiaoming Li | x.m.li@hotmail.com Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing; Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.

Abstract

The exploration of bone repair materials has been continuously carried out. After several decades of development, bone repair materials have experienced from traditional ceramics, metals and polymers to modern smart hydrogels and multifunctional composite materials, etc. At the same time of designing and preparing the novel materials, more and more attention has been paid to their osteogenesis mechanism and immune response. The development of next generation of bone repair materials requires the comprehensive consideration of a combination of many related factors. This article reviews the research status and the progress of bone repair materials from the three aspects, current most-used types, bioactive mechanism and updated related investigations. Finally, several research points that are crucial for the further development of bone repairs are proposed in the conclusion and perspectives part.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2019-02-21
Info
Issue
Section
Reviews
Keywords:
bone repair material, bone tissue engineering, bioactive mechanism, immune response
Statistics
  • Abstract views: 341

  • PDF: 195
How to Cite
He, Y., He, W., Fan, Y., & Li, X. (2019). Materials for bone regeneration: Current types, bioactive mechanism and updated investigations. BioMaterials Advances, 2(1). https://doi.org/10.4081/bioadv.2019.63