Original articles
28 September 2021
Vol. 3 No. 1 (2022)
https://doi.org/10.4081/bse.133

Rigenera protocol: Elucidation of the mechanisms involved in wound healing

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Wound healing, autologous micrografts, skin regeneration, ERK pathway
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Authors

Gabriele Ceccarelli
gabriele.ceccarelli@unipv.it
Department of Public Health, Experimental Medicine and Forensic, University of Pavia, Pavia; Centre of Health Technologies, University of Pavia, Pavia, Italy; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium, Italy.
Martina Balli
Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium.
Riccardo Bellazzi
Centre of Health Technologies, University of Pavia, Pavia, Italy; Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy.
Maurilio Sampaolesi
Department of Public Health, Experimental Medicine and Forensic, University of Pavia, Pavia; Centre of Health Technologies, University of Pavia, Pavia, Italy; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium.
Gabriella Cusella
Department of Public Health, Experimental Medicine and Forensic, University of Pavia, Pavia; Centre of Health Technologies, University of Pavia, Pavia, Italy.

In this study, we show an approach that follow 3R guidelines in order to demonstrate how Autologous Micrografts (AMG) modulates primary fibroblast migration and accelerates skin re-epithelialization without affecting cell proliferation.

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Rigenera protocol: Elucidation of the mechanisms involved in wound healing. (2021). Biomedical Science and Engineering, 3(1). https://doi.org/10.4081/bse.133
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